It's over. Hostess is no more. You have 3 options:
1 - Drive to Canada. Hostess is separate up there so they're still pumpin 'em out.
2 - Ebay. There are currently over 20,000 listings for Twinkies.
3 - Make your own! Here's the recipe.
This recipe yields 12 full-sized Twinkies, or 24 minis.